Single-Channel Analysis: An Introduction
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چکیده
Patch-clamp recordings of single-channel activity are measurements of the current flowing through an ion channel over time. These recordings are distinctive, because they generally show sudden transitions between two welldefined levels of current flow. The two levels of current flow are normally interpreted as representing closed and open states of an ion channel. The transitions appear to be sudden, because they occur far more quickly than can be resolved by the recording system.
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